SFTPC Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Lipid-binding
Chromosomal Location of mouse Ortholog: 14 D2|14 36.32 cM
Cellular Component:  alveolar lamellar body; cytoplasm; extracellular region; extracellular space; multivesicular body
Molecular Function:  identical protein binding; protein homodimerization activity
Biological Process:  protein homooligomerization
Reference #:  P21841 (UniProtKB)
Alt. Names/Synonyms: Bric; Bricd6; pro-SpC; PSPC; Pulmonary surfactant-associated protein C; Pulmonary surfactant-associated proteolipid SPL(Val); Sft; Sftp; Sftp-2; Sftp2; Sftpc; SP-C; SP5; SPC; surfactant associated protein C
Gene Symbols: Sftpc
Molecular weight: 21,055 Da
Basal Isoelectric point: 6.42  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene