HMGN2 Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Belongs to the HMGN family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1p36.11
Cellular Component:  chromatin; cytoplasm; extracellular space; nucleus
Molecular Function:  nucleosomal DNA binding; protein binding
Biological Process:  antimicrobial humoral immune response mediated by antimicrobial peptide; killing of cells of other organism
Reference #:  P05204 (UniProtKB)
Alt. Names/Synonyms: high mobility group nucleosomal binding domain 2; High mobility group nucleosome-binding domain-containing protein 2; high mobility group protein N2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; HMG17; HMGN2; MGC5629; MGC88718; Non-histone chromosomal protein HMG-17; nonhistone chromosomal protein HMG-17
Gene Symbols: HMGN2
Molecular weight: 9,393 Da
Basal Isoelectric point: 10  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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HMGN2

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene