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SRP9
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. Belongs to the SRP9 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding; Translation |
| Chromosomal Location of human Ortholog: 1q42.12 |
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Cellular Component:
cytosol; signal recognition particle receptor complex; signal recognition particle, endoplasmic reticulum targeting
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Molecular Function:
7S RNA binding; protein binding; RNA binding; signal recognition particle binding
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Biological Process:
negative regulation of translational elongation; SRP-dependent cotranslational protein targeting to membrane
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Reference #:
P49458
(UniProtKB)
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Alt. Names/Synonyms: ALURBP; MGC110981; signal recognition particle 9; Signal recognition particle 9 kDa protein; signal recognition particle 9kD; signal recognition particle 9kDa; SRP09; SRP9
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Gene Symbols: SRP9
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Molecular weight:
10,112 Da
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Basal Isoelectric point:
7.76
Predict pI for various phosphorylation states
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