SRP9 Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. Belongs to the SRP9 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA-binding; Translation
Chromosomal Location of Human Ortholog: 1q42.12
Cellular Component:  cytosol; signal recognition particle receptor complex; signal recognition particle, endoplasmic reticulum targeting
Molecular Function:  7S RNA binding; protein binding; RNA binding; signal recognition particle binding
Biological Process:  negative regulation of translational elongation; SRP-dependent cotranslational protein targeting to membrane
Reference #:  P49458 (UniProtKB)
Alt. Names/Synonyms: ALURBP; MGC110981; signal recognition particle 9; Signal recognition particle 9 kDa protein; signal recognition particle 9kD; signal recognition particle 9kDa; SRP09; SRP9
Gene Symbols: SRP9
Molecular weight: 10,112 Da
Basal Isoelectric point: 7.76  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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