EXOC7
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. Belongs to the EXO70 family. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Cytoskeletal |
Chromosomal Location of human Ortholog: 17q25.1 |
Cellular Component:
centriolar satellite; cytosol; exocyst; Flemming body; growth cone membrane; microtubule organizing center; plasma membrane
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Molecular Function:
phosphatidylinositol-4,5-bisphosphate binding; protein binding
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Biological Process:
exocytosis; membrane fission; mitotic cytokinesis; protein transport; regulation of entry of bacterium into host cell; regulation of macroautophagy; vesicle docking involved in exocytosis; vesicle tethering involved in exocytosis
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Disease: Neurodevelopmental Disorder With Seizures And Brain Atrophy
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Reference #:
Q9UPT5
(UniProtKB)
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Alt. Names/Synonyms: 2-5-3p; BLOM4; DKFZp686J04253; EX070; EXO70; Exo70p; EXOC1; EXOC7; Exocyst complex component 7; Exocyst complex component Exo70; FLJ40965; FLJ46415; KIAA1067; YJL085W
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Gene Symbols: EXOC7
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Molecular weight:
83,382 Da
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Basal Isoelectric point:
6.33
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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