EXOC7 Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. Belongs to the EXO70 family. 6 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component:  cytosol; exocyst; Flemming body; microtubule organizing center; plasma membrane
Molecular Function:  protein binding
Biological Process:  exocytosis; protein transport; regulation of entry of bacterium into host cell; regulation of macroautophagy
Reference #:  Q9UPT5 (UniProtKB)
Alt. Names/Synonyms: 2-5-3p; DKFZp686J04253; EX070; EXO70; Exo70p; EXOC1; EXOC7; Exocyst complex component 7; Exocyst complex component Exo70; FLJ40965; FLJ46415; KIAA1067; YJL085W
Gene Symbols: EXOC7
Molecular weight: 83,382 Da
Basal Isoelectric point: 6.33  Predict pI for various phosphorylation states
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EXOC7

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein