FBXW2 Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of mouse Ortholog: 2|2 B
Cellular Component:  cytoplasm; nucleus
Molecular Function:  protein binding
Reference #:  Q60584 (UniProtKB)
Alt. Names/Synonyms: 2700071L08Rik; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; F-box/WD repeat-containing protein 2; FBW2; Fbxw2; Fwd2; MD6; OTTMUSP00000012913; OTTMUSP00000012915; OTTMUSP00000012918; Protein MD6
Gene Symbols: Fbxw2
Molecular weight: 47,896 Da
Basal Isoelectric point: 6.32  Predict pI for various phosphorylation states
Select Structure to View Below

FBXW2

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene