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FBXW2
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Ubiquitin conjugating system |
| Chromosomal Location of Human Ortholog: 9q33.2 |
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Cellular Component:
cytosol
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Molecular Function:
protein binding; ubiquitin-protein transferase activity
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Biological Process:
cellular protein modification process; post-translational protein modification; protein polyubiquitination; proteolysis
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Reference #:
Q9UKT8
(UniProtKB)
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Alt. Names/Synonyms: F-box and WD repeat domain containing 2; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; F-box/WD repeat-containing protein 2; FBW2; FBXW2; FWD2; Md6; MGC117371; Protein MD6
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Gene Symbols: FBXW2
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Molecular weight:
51,512 Da
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Basal Isoelectric point:
6.11
Predict pI for various phosphorylation states
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