ACO2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Belongs to the aconitase/IPM isomerase family. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - citrate (TCA) cycle; Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 4.2.1.3; Lyase; Mitochondrial
Chromosomal Location of Human Ortholog: 15|15 E1
Cellular Component:  cytosol; mitochondrion
Molecular Function:  3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; aconitate hydratase activity; iron ion binding; iron-sulfur cluster binding; lyase activity; metal ion binding
Biological Process:  citrate metabolic process; isocitrate metabolic process; tricarboxylic acid cycle
Reference #:  Q99KI0 (UniProtKB)
Alt. Names/Synonyms: Aco-2; Aco2; Aco3; ACON; Aconitase; aconitase 2, mitochondrial; Aconitate hydratase, mitochondrial; Citrate hydro-lyase; D10Wsu183e; OTTMUSP00000017637
Gene Symbols: Aco2
Molecular weight: 85,464 Da
Basal Isoelectric point: 8.08  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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ACO2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene