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ZNF638
Early regulator of adipogenesis that works as a transcription cofactor of CEBPs, controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1. Binds to cytidine clusters in double-stranded DNA. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding; RNA-binding |
| Chromosomal Location of Human Ortholog: 6|6 C3 |
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Cellular Component:
intracellular membrane-bound organelle; nucleoplasm; nucleus
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Molecular Function:
DNA binding; metal ion binding; nucleic acid binding; RNA binding; zinc ion binding
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Biological Process:
regulation of transcription, DNA-templated; RNA splicing; transcription, DNA-dependent
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Reference #:
Q61464
(UniProtKB)
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Alt. Names/Synonyms: AI323587; mNP220; Np220; Nuclear protein 220; Zfml; Zinc finger matrin-like protein; Zinc finger protein 638; zinc finger, matrin-like; ZN638; Znf638
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Gene Symbols: Znf638
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Molecular weight:
218,134 Da
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Basal Isoelectric point:
6.46
Predict pI for various phosphorylation states
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