WDR9 an ubiquitously expressed WD40 repeat protein that may be a transcriptional activator and be involved in chromatin remodeling. Interacts with SMARCA4. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 21q22.2
Cellular Component:  cytosol; nucleolus; nucleoplasm
Biological Process:  chromatin organization; cytoskeleton organization; interleukin-7-mediated signaling pathway; regulation of cell shape
Reference #:  Q9NSI6 (UniProtKB)
Alt. Names/Synonyms: bromodomain and WD repeat domain containing 1; Bromodomain and WD repeat-containing protein 1; BRWD1; C21orf107; cAMP response element binding and beta-tranducin family-like; FLJ43918; N143; transcriptional unit N143; WD repeat domain 9; WD repeat protein WDR9-form2; WD repeat-containing protein 9; WDR9
Gene Symbols: BRWD1
Molecular weight: 262,936 Da
Basal Isoelectric point: 8.73  Predict pI for various phosphorylation states
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WDR9

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein