TSGA14 Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. Belongs to the CEP41 family. Isoform 1 and isoform 4 are expressed in testis and fetal tissues. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 7q32.2
Cellular Component:  centriole; centrosome; ciliary basal body; cilium; cytosol
Molecular Function:  protein binding
Biological Process:  ciliary basal body-plasma membrane docking; cilium assembly; G2/M transition of mitotic cell cycle; protein polyglutamylation; protein transport; regulation of G2/M transition of mitotic cell cycle
Disease: Joubert Syndrome 15
Reference #:  Q9BYV8 (UniProtKB)
Alt. Names/Synonyms: centrosomal protein 41; centrosomal protein 41 kDa; centrosomal protein 41kDa; Centrosomal protein of 41 kDa; CEP41; DKFZp762H1311; JBTS15; testis specific protein A14; testis specific, 14; Testis-specific gene A14 protein; TSGA14
Gene Symbols: CEP41
Molecular weight: 41,368 Da
Basal Isoelectric point: 8.46  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene