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TSGA14
Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. Belongs to the CEP41 family. Isoform 1 and isoform 4 are expressed in testis and fetal tissues. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 7q32.2 |
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Cellular Component:
centriole; centrosome; ciliary basal body; cilium; cytosol
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Molecular Function:
protein binding
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Biological Process:
cilium assembly; protein polyglutamylation; protein transport
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Disease: Joubert Syndrome 15
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Reference #:
Q9BYV8
(UniProtKB)
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Alt. Names/Synonyms: centrosomal protein 41; centrosomal protein 41 kDa; centrosomal protein 41kDa; Centrosomal protein of 41 kDa; CEP41; DKFZp762H1311; JBTS15; testis specific protein A14; testis specific, 14; Testis-specific gene A14 protein; TSGA14
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Gene Symbols: CEP41
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Molecular weight:
41,368 Da
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Basal Isoelectric point:
8.46
Predict pI for various phosphorylation states
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