|
TMOD3
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. Belongs to the tropomodulin family. Ubiquitous. Note: This description may include information from UniProtKB.
|
| Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of human Ortholog: 15q21.2 |
|
Cellular Component:
cytoskeleton; myofibril; striated muscle thin filament
|
|
Molecular Function:
actin binding; tropomyosin binding
|
|
Biological Process:
actin filament organization; cell-cell adhesion; erythrocyte development; mitotic cell cycle phase transition; muscle contraction; myofibril assembly; pointed-end actin filament capping; positive regulation of mitotic cell cycle phase transition
|
|
Reference #:
Q9NYL9
(UniProtKB)
|
|
Alt. Names/Synonyms: TMOD3; tropomodulin 3; tropomodulin 3 (ubiquitous); Tropomodulin-3; U-Tmod; Ubiquitous tropomodulin; UTMOD
|
|
Gene Symbols: TMOD3
|
|
Molecular weight:
39,595 Da
|
|
Basal Isoelectric point:
5.08
Predict pI for various phosphorylation states
|
|
CST Pathways:
Actin Dynamics
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|
