TMOD3 Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. Belongs to the tropomodulin family. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15q21.2
Cellular Component: 
Molecular Function:  actin binding
Biological Process:  cell-cell adhesion; erythrocyte development; pointed-end actin filament capping; positive regulation of mitotic cell cycle phase transition
Reference #:  Q9NYL9 (UniProtKB)
Alt. Names/Synonyms: TMOD3; tropomodulin 3; tropomodulin 3 (ubiquitous); Tropomodulin-3; U-Tmod; Ubiquitous tropomodulin; UTMOD
Gene Symbols: TMOD3
Molecular weight: 39,595 Da
Basal Isoelectric point: 5.08  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB