SEPT5 Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. Expressed at high levels in the CNS, as well as in heart and platelets (at protein level). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase; Vesicle
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component:  plasma membrane; septin complex; synaptic vesicle
Molecular Function:  GTP binding; GTPase activity; protein binding; structural molecule activity
Biological Process:  adult behavior; regulation of exocytosis; regulation of synaptic vesicle exocytosis; social behavior; synaptic vesicle targeting
Reference #:  Q99719 (UniProtKB)
Alt. Names/Synonyms: CDCREL; CDCrel-1; CDCREL1; cell division control related protein 1; Cell division control-related protein 1; H5; peanut-like 1; Peanut-like protein 1; platelet glycoprotein Ib beta chain; PNUTL1; SEPT5; septin 5; Septin-5
Gene Symbols: SEPT5
Molecular weight: 42,777 Da
Basal Isoelectric point: 6.21  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB