OSTF1 Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. Ubiquitously expressed. Present in osteoclasts (at protein level). Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9q21.13
Cellular Component:  extracellular region; ficolin-1-rich granule lumen; secretory granule lumen
Molecular Function:  protein binding; SH3 domain binding
Biological Process:  neutrophil degranulation; ossification; signal transduction
Reference #:  Q92882 (UniProtKB)
Alt. Names/Synonyms: bA235O14.1; FLJ20559; OSF; osteoclast stimulating factor 1; Osteoclast-stimulating factor 1; OSTF1; SH3P2
Gene Symbols: OSTF1
Molecular weight: 23,787 Da
Basal Isoelectric point: 5.46  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene