AKAP4 Major structural component of sperm fibrous sheath. Plays a role in sperm motility. Belongs to the AKAP110 family. Testis specific; only expressed in round spermatids. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: X A1.1|X 3.17 cM
Cellular Component:  cell projection; cilium; cytoplasm; motile cilium; perinuclear region of cytoplasm; sperm fibrous sheath; sperm principal piece; Z disc
Molecular Function:  protein binding; protein kinase A binding
Biological Process:  cell projection organization; establishment of protein localization; flagellated sperm motility; motile cilium assembly; protein localization; transmembrane receptor protein serine/threonine kinase signaling pathway
Reference #:  Q60662 (UniProtKB)
Alt. Names/Synonyms: A kinase (PRKA) anchor protein 4; A kinase anchoring protein 4; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; AKAP 82; AKAP-4; Akap4; Akap82; CT99; Fsc; FSC1; Major sperm fibrous sheath protein; mAKAP82; OTTMUSP00000017697; OTTMUSP00000017742; p82; PRKA4; Protein kinase A-anchoring protein 4
Gene Symbols: Akap4
Molecular weight: 93,796 Da
Basal Isoelectric point: 6.55  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene