HINT1 Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha- acetyl lysine methyl ester and AMP-NH2. Belongs to the HINT family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; EC 3.-.-.-; Hydrolase
Chromosomal Location of Human Ortholog: 5q23.3
Cellular Component:  cytoskeleton; cytosol; histone deacetylase complex; nucleus; plasma membrane
Molecular Function:  hydrolase activity; nucleotide binding; protein kinase C binding
Biological Process:  intrinsic apoptotic signaling pathway by p53 class mediator; positive regulation of calcium-mediated signaling; purine ribonucleotide catabolic process; regulation of transcription, DNA-templated; signal transduction
Disease: Neuromyotonia And Axonal Neuropathy, Autosomal Recessive
Reference #:  P49773 (UniProtKB)
Alt. Names/Synonyms: Adenosine 5'-monophosphoramidase; FLJ30414; FLJ32340; HINT; HINT1; histidine triad nucleotide binding protein 1; Histidine triad nucleotide-binding protein 1; PKCI-1; PKCI1; PRKCNH1; Protein kinase C inhibitor 1; Protein kinase C-interacting protein 1
Gene Symbols: HINT1
Molecular weight: 13,802 Da
Basal Isoelectric point: 6.43  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene