AVEN Protects against apoptosis mediated by Apaf-1. Binds Apaf-1, BCL-2 and BAD (Bcl-xl). Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Inhibitor
Chromosomal Location of Human Ortholog: 15q14
Cellular Component:  cytosol; endomembrane system; membrane
Molecular Function:  protein binding
Biological Process:  apoptotic process; negative regulation of apoptotic process
Reference #:  Q9NQS1 (UniProtKB)
Alt. Names/Synonyms: apoptosis, caspase activation inhibitor; AVEN; Cell death regulator Aven; PDCD12; programmed cell death 12
Gene Symbols: AVEN
Molecular weight: 38,506 Da
Basal Isoelectric point: 4.9  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB