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AVEN
Protects against apoptosis mediated by Apaf-1. Binds Apaf-1, BCL-2 and BAD (Bcl-xl). Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas. Note: This description may include information from UniProtKB.
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| Protein type: Apoptosis; Inhibitor |
| Chromosomal Location of Human Ortholog: 15q14 |
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Cellular Component:
cytosol; endomembrane system; membrane
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Molecular Function:
protein binding
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Biological Process:
apoptotic process; negative regulation of apoptotic process
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Reference #:
Q9NQS1
(UniProtKB)
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Alt. Names/Synonyms: apoptosis, caspase activation inhibitor; AVEN; Cell death regulator Aven; PDCD12; programmed cell death 12
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Gene Symbols: AVEN
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Molecular weight:
38,506 Da
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Basal Isoelectric point:
4.9
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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