GTF3C5 Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. Belongs to the TFIIIC subunit 5 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription initiation complex
Chromosomal Location of Human Ortholog: 2|2 A3
Cellular Component:  nucleoplasm; nucleus; transcription factor TFIIIC complex
Molecular Function:  DNA binding
Biological Process:  skeletal muscle cell differentiation; transcription initiation from RNA polymerase III promoter
Reference #:  Q8R2T8 (UniProtKB)
Alt. Names/Synonyms: 2700084A09Rik; General transcription factor 3C polypeptide 5; general transcription factor III polypeptide 5; general transcription factor IIIC, polypeptide 5; Gtf3c5; OTTMUSP00000012430; TF3C-epsilon; TF3C5; TFIIIC 63 kDa subunit; TFiiiC2-63; TFIIIC63; TFIIICepsilon; Transcription factor IIIC 63 kDa subunit; Transcription factor IIIC subunit epsilon
Gene Symbols: Gtf3c5
Molecular weight: 60,502 Da
Basal Isoelectric point: 6.29  Predict pI for various phosphorylation states
Select Structure to View Below

GTF3C5

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene