GTF3C5 Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. Belongs to the TFIIIC subunit 5 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription initiation complex
Chromosomal Location of Human Ortholog: 9q34.13
Cellular Component:  nucleoplasm; transcription factor TFIIIC complex
Molecular Function:  protein binding
Biological Process:  5S class rRNA transcription by RNA polymerase III; RNA polymerase III preinitiation complex assembly; skeletal muscle cell differentiation; transcription by RNA polymerase III; tRNA transcription by RNA polymerase III
Reference #:  Q9Y5Q8 (UniProtKB)
Alt. Names/Synonyms: FLJ20857; General transcription factor 3C polypeptide 5; general transcription factor IIIC subunit 5; general transcription factor IIIC, polypeptide 5, 63kDa; GTF3C5; TF3C-epsilon; TF3C5; TFIIIC 63 kDa subunit; TFiiiC2-63; TFIIIC63; TFIIICepsilon; Transcription factor IIIC 63 kDa subunit; Transcription factor IIIC subunit epsilon; transcription factor IIIC, 63 kD
Gene Symbols: GTF3C5
Molecular weight: 59,571 Da
Basal Isoelectric point: 6.47  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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