PARP4 Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas. Note: This description may include information from UniProtKB.
Protein type: EC; Transferase
Chromosomal Location of Human Ortholog: 14|14 C3
Cellular Component:  cytoplasm; cytosol; nucleus; spindle; spindle microtubule
Molecular Function:  enzyme binding; NAD+ ADP-ribosyltransferase activity; protein ADP-ribosylase activity; transferase activity; transferase activity, transferring glycosyl groups
Biological Process:  cell death; cellular protein modification process; inflammatory response; protein ADP-ribosylation; regulation of telomerase activity
Reference #:  E9PYK3 (UniProtKB)
Alt. Names/Synonyms: ADP-ribosyltransferase diphtheria toxin-like 4; Adprtl1; ARTD4; C030027K23Rik; E230037B21Rik; Gm743; mKIAA0177; p193; Parp4; PARPL; PH5P; poly (ADP-ribose) polymerase family, member 4; poly (ADP-ribose) polymerase)-like 1; Poly [ADP-ribose] polymerase 4; Protein mono-ADP-ribosyltransferase PARP4; Vault poly(ADP-ribose) polymerase; VAULT3; VPARP
Gene Symbols: Parp4
Molecular weight: 216,133 Da
Basal Isoelectric point: 5.71  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein