|
PARP4
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas. Note: This description may include information from UniProtKB.
|
| Protein type: EC 2.4.2.30; Transferase |
| Chromosomal Location of Human Ortholog: 14|14 C3 |
|
Cellular Component:
cytoplasm; cytosol; nucleus; spindle; spindle microtubule
|
|
Molecular Function:
enzyme binding; NAD+ ADP-ribosyltransferase activity; protein ADP-ribosylase activity; transferase activity; transferase activity, transferring glycosyl groups
|
|
Biological Process:
cell death; cellular protein modification process; inflammatory response; protein ADP-ribosylation; regulation of telomerase activity
|
|
Reference #:
E9PYK3
(UniProtKB)
|
|
Alt. Names/Synonyms: ADP-ribosyltransferase diphtheria toxin-like 4; Adprtl1; ARTD4; C030027K23Rik; E230037B21Rik; Gm743; mKIAA0177; p193; Parp4; PARPL; PH5P; poly (ADP-ribose) polymerase family, member 4; poly (ADP-ribose) polymerase)-like 1; Poly [ADP-ribose] polymerase 4; Protein mono-ADP-ribosyltransferase PARP4; Vault poly(ADP-ribose) polymerase; VAULT3; VPARP
|
|
Gene Symbols: Parp4
|
|
Molecular weight:
216,133 Da
|
|
Basal Isoelectric point:
5.71
Predict pI for various phosphorylation states
|
