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PARP4
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.4.2.30; Transferase |
| Chromosomal Location of mouse Ortholog: 14|14 C3 |
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Cellular Component:
cytoplasm; cytosol; nucleoplasm; nucleus; spindle; spindle microtubule
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Molecular Function:
enzyme binding; glycosyltransferase activity; NAD+ ADP-ribosyltransferase activity; NAD+-protein ADP-ribosyltransferase activity; nucleotidyltransferase activity; transferase activity
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Biological Process:
cell death; inflammatory response; protein modification process; regulation of telomerase activity; telomere maintenance via telomerase
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Reference #:
E9PYK3
(UniProtKB)
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Alt. Names/Synonyms: Adp; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase diphtheria toxin-like 4; Adprtl1; ARTD4; C030027K23Rik; E230037B21Rik; Gm743; Kiaa0177; mKIAA0177; mVparp; p19; p193; PARP-4; Parp4; PARPL; PH5P; poly (ADP-ribose) polymerase family, member 4; poly (ADP-ribose) polymerase)-like 1; Poly [ADP-ribose] polymerase 4; Protein mono-ADP-ribosyltransferase PARP4; VAU; Vault poly(ADP-ribose) polymerase; VAULT3; VPARP
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Gene Symbols: Parp4
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Molecular weight:
216,133 Da
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Basal Isoelectric point:
5.71
Predict pI for various phosphorylation states
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