PARP4 Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas. Note: This description may include information from UniProtKB.
Protein type: EC; Transferase
Chromosomal Location of mouse Ortholog: 14|14 C3
Cellular Component:  cytoplasm; cytosol; nucleoplasm; nucleus; spindle; spindle microtubule
Molecular Function:  enzyme binding; glycosyltransferase activity; NAD+ ADP-ribosyltransferase activity; NAD+-protein ADP-ribosyltransferase activity; nucleotidyltransferase activity; transferase activity
Biological Process:  cell death; inflammatory response; protein modification process; regulation of telomerase activity; telomere maintenance via telomerase
Reference #:  E9PYK3 (UniProtKB)
Alt. Names/Synonyms: Adp; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase diphtheria toxin-like 4; Adprtl1; ARTD4; C030027K23Rik; E230037B21Rik; Gm743; Kiaa0177; mKIAA0177; mVparp; p19; p193; PARP-4; Parp4; PARPL; PH5P; poly (ADP-ribose) polymerase family, member 4; poly (ADP-ribose) polymerase)-like 1; Poly [ADP-ribose] polymerase 4; Protein mono-ADP-ribosyltransferase PARP4; VAU; Vault poly(ADP-ribose) polymerase; VAULT3; VPARP
Gene Symbols: Parp4
Molecular weight: 216,133 Da
Basal Isoelectric point: 5.71  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein