NAA15 The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Acetyltransferase
Chromosomal Location of Human Ortholog: 4q31.1
Cellular Component:  cytoplasm; cytosol; NatA complex; nucleus; transcription factor complex
Molecular Function:  protein binding; ribosome binding
Biological Process:  angiogenesis; cell differentiation; N-terminal protein amino acid acetylation; negative regulation of apoptotic process; positive regulation of transcription, DNA-templated; protein stabilization
Disease: Mental Retardation, Autosomal Dominant 50
Reference #:  Q9BXJ9 (UniProtKB)
Alt. Names/Synonyms: GA19; Gastric cancer antigen Ga19; N(alpha)-acetyltransferase 15, NatA auxiliary subunit; N-alpha-acetyltransferase 15, NatA auxiliary subunit; N-terminal acetyltransferase; NAA15; NARG1; NATH; NMDA receptor regulated 1; NMDA receptor-regulated protein 1; Protein tubedown-1; TBDN100; transcriptional coactivator tubedown-100; tubedown-1
Gene Symbols: NAA15
Molecular weight: 101,272 Da
Basal Isoelectric point: 7.23  Predict pI for various phosphorylation states
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NAA15

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein