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GUK1
Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.4.8; Kinase, other; Nucleotide Metabolism - purine |
| Chromosomal Location of Human Ortholog: 1q42.13 |
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Cellular Component:
cytosol
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Molecular Function:
ATP binding; guanylate kinase activity
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Biological Process:
ATP metabolic process; dATP metabolic process; dGDP biosynthetic process; dGMP metabolic process; GDP biosynthetic process; GDP-mannose metabolic process; glycoprotein transport; GMP metabolic process; nucleobase-containing small molecule interconversion; nucleotide phosphorylation; purine nucleotide metabolic process
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Reference #:
Q16774
(UniProtKB)
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Alt. Names/Synonyms: FLJ42686; FLJ43710; GMK; GMP kinase; Guanylate kinase; guanylate kinase 1; GUK1; KGUA
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Gene Symbols: GUK1
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Molecular weight:
21,726 Da
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Basal Isoelectric point:
6.11
Predict pI for various phosphorylation states
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