|
GUK1
Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
|
| Protein type: EC 2.7.4.8; Kinase, other; Nucleotide Metabolism - purine |
| Chromosomal Location of Human Ortholog: 1q42.13 |
|
Cellular Component:
cytosol
|
|
Molecular Function:
ATP binding; guanylate kinase activity
|
|
Biological Process:
ATP metabolic process; dATP metabolic process; dGDP biosynthetic process; dGMP metabolic process; GDP biosynthetic process; GDP-mannose metabolic process; GMP metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleotide phosphorylation; purine nucleotide metabolic process
|
|
Reference #:
Q16774
(UniProtKB)
|
|
Alt. Names/Synonyms: FLJ42686; FLJ43710; GMK; GMP kinase; Guanylate kinase; guanylate kinase 1; GUK1; KGUA
|
|
Gene Symbols: GUK1
|
|
Molecular weight:
21,726 Da
|
|
Basal Isoelectric point:
6.11
Predict pI for various phosphorylation states
|
