GUK1 Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.4.8; Kinase, other; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 1q42.13
Cellular Component:  cytosol
Molecular Function:  ATP binding; guanylate kinase activity
Biological Process:  ATP metabolic process; dATP metabolic process; dGDP biosynthetic process; dGMP metabolic process; GDP biosynthetic process; GDP-mannose metabolic process; glycoprotein transport; GMP metabolic process; nucleobase-containing small molecule interconversion; nucleotide phosphorylation; purine nucleotide metabolic process
Reference #:  Q16774 (UniProtKB)
Alt. Names/Synonyms: FLJ42686; FLJ43710; GMK; GMP kinase; Guanylate kinase; guanylate kinase 1; GUK1; KGUA
Gene Symbols: GUK1
Molecular weight: 21,726 Da
Basal Isoelectric point: 6.11  Predict pI for various phosphorylation states
Select Structure to View Below

GUK1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein