GUK1 Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC; Kinase, other; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 1q42.13
Cellular Component:  cytosol
Molecular Function:  ATP binding; guanylate kinase activity
Biological Process:  ATP metabolic process; dATP metabolic process; dGDP biosynthetic process; dGMP metabolic process; GDP biosynthetic process; GDP-mannose metabolic process; glycoprotein transport; GMP metabolic process; nucleobase-containing small molecule interconversion; nucleotide phosphorylation; purine nucleotide metabolic process
Reference #:  Q16774 (UniProtKB)
Alt. Names/Synonyms: FLJ42686; FLJ43710; GMK; GMP kinase; Guanylate kinase; guanylate kinase 1; GUK1; KGUA
Gene Symbols: GUK1
Molecular weight: 21,726 Da
Basal Isoelectric point: 6.11  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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