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PMPCB
Catalytic subunit of the essential mitochondrial processing protease (MPP), which is required for maturation of the majority of mitochondrial precursor proteins. Most MPP cleavage sites follow an arginine at position -2. Belongs to the peptidase M16 family. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.4.24.64; Mitochondrial; Protease |
| Chromosomal Location of Human Ortholog: 7q22.1 |
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Cellular Component:
mitochondrial inner membrane; mitochondrion
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Molecular Function:
metal ion binding; metalloendopeptidase activity
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Biological Process:
mitochondrial calcium ion transmembrane transport
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Disease: Multiple Mitochondrial Dysfunctions Syndrome 6
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Reference #:
O75439
(UniProtKB)
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Alt. Names/Synonyms: Beta-MPP; MAS1; mitochondrial processing peptidase beta subunit; Mitochondrial-processing peptidase subunit beta; MPP11; MPPB; MPPP52; P-52; peptidase (mitochondrial processing) beta; peptidase, mitochondrial processing beta subunit; peptidase, mitochondrial processing subunit beta; PMPCB
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Gene Symbols: PMPCB
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Molecular weight:
54,366 Da
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Basal Isoelectric point:
6.38
Predict pI for various phosphorylation states
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