PMPCB Cleaves presequences (transit peptides) from mitochondrial protein precursors. Belongs to the peptidase M16 family. Note: This description may include information from UniProtKB.
Protein type: EC; Mitochondrial; Protease
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component:  mitochondrial inner membrane; mitochondrion
Molecular Function:  metal ion binding; metalloendopeptidase activity
Biological Process:  mitochondrial calcium ion transmembrane transport
Disease: Multiple Mitochondrial Dysfunctions Syndrome 6
Reference #:  O75439 (UniProtKB)
Alt. Names/Synonyms: Beta-MPP; mitochondrial processing peptidase beta subunit; Mitochondrial-processing peptidase subunit beta; MPP11; MPPB; MPPP52; P-52; peptidase (mitochondrial processing) beta; PMPCB
Gene Symbols: PMPCB
Molecular weight: 54,366 Da
Basal Isoelectric point: 6.38  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene