PMPCB Catalytic subunit of the essential mitochondrial processing protease (MPP), which is required for maturation of the majority of mitochondrial precursor proteins. Most MPP cleavage sites follow an arginine at position -2. Belongs to the peptidase M16 family. Note: This description may include information from UniProtKB.
Protein type: EC 3.4.24.64; Mitochondrial; Protease
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component:  mitochondrial inner membrane; mitochondrion
Molecular Function:  metal ion binding; metalloendopeptidase activity
Biological Process:  mitochondrial calcium ion transmembrane transport
Disease: Multiple Mitochondrial Dysfunctions Syndrome 6
Reference #:  O75439 (UniProtKB)
Alt. Names/Synonyms: Beta-MPP; MAS1; mitochondrial processing peptidase beta subunit; Mitochondrial-processing peptidase subunit beta; MPP11; MPPB; MPPP52; P-52; peptidase (mitochondrial processing) beta; peptidase, mitochondrial processing beta subunit; peptidase, mitochondrial processing subunit beta; PMPCB
Gene Symbols: PMPCB
Molecular weight: 54,366 Da
Basal Isoelectric point: 6.38  Predict pI for various phosphorylation states
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PMPCB

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene