CDH18 Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of human Ortholog: 5p14.3
Cellular Component:  adherens junction; catenin complex; plasma membrane
Molecular Function:  cadherin binding; calcium ion binding
Biological Process:  adherens junction organization; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell morphogenesis; cell-cell adhesion mediated by cadherin; cell-cell junction assembly; homophilic cell adhesion via plasma membrane adhesion molecules; multicellular organism development
Reference #:  Q13634 (UniProtKB)
Alt. Names/Synonyms: CAD18; cadherin 18; cadherin 18, type 2; Cadherin-14; Cadherin-18; cadherin-like 24; CDH14; CDH14L; CDH18; CDH24; ey-cadherin
Gene Symbols: CDH18
Molecular weight: 88,073 Da
Basal Isoelectric point: 4.98  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein