KLC2 Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Belongs to the kinesin light chain family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motor
Chromosomal Location of mouse Ortholog: 19 A|19 4.25 cM
Cellular Component:  ciliary rootlet; cytoplasm; cytoskeleton; cytosol; kinesin complex; lysosome; membrane; microtubule; mitochondrion; neuron projection; nucleoplasm; plasma membrane; protein-containing complex
Molecular Function:  kinesin binding; protein binding
Biological Process:  axo-dendritic transport; lysosome localization; microtubule-based movement
Reference #:  O88448 (UniProtKB)
Alt. Names/Synonyms: 8030455F02Rik; AW212649; Kinesin light chain 2; KLC 2; KLC-2; Klc2; Klc2 protein; OTTMUSP00000017579
Gene Symbols: Klc2
Molecular weight: 66,662 Da
Basal Isoelectric point: 6.77  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  Ensembl Protein