MASK-BP3 May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases. Belongs to the mask family. Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of human Ortholog: 5q31.3
Cellular Component: 
Reference #:  Q8IWZ3-6 (UniProtKB)
Alt. Names/Synonyms: ANKH1; ANKHD1; ANKHD1-EIF4EBP3; ANKHD1-EIF4EBP3 protein; ANKHD1-EIF4EBP3 readthrough; Ankyrin repeat and KH domain-containing protein 1; HCG2045902, isoform CRA_b; HIV-1 Vpr-binding ankyrin repeat protein; hMASK; KIAA1085; MASK; MASK-4E-BP3 alternate reading frame; MASK-BP3; MASK-BP3arf; Multiple ankyrin repeats single KH domain; Multiple ankyrin repeats single KH domain protein isoform 2; VBARP
Gene Symbols: ANKHD1-EIF4EBP3
Molecular weight: 277,175 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein