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LRGUK
Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.4.8; Kinase, other |
| Chromosomal Location of mouse Ortholog: 6|6 A3.3 |
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Cellular Component:
acrosomal vesicle; cell projection; cytoplasm; cytoplasmic vesicle; cytoskeleton; cytosol; manchette
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Molecular Function:
ATP binding; guanylate kinase activity; kinase activity; nucleotide binding; protein binding; transferase activity
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Biological Process:
axoneme assembly; cell differentiation; phosphorylation; spermatogenesis
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Reference #:
Q9D5S7
(UniProtKB)
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Alt. Names/Synonyms: 4921528H16Rik; Leucine-rich repeat and guanylate kinase domain-containing protein; leucine-rich repeats and guanylate kinase domain containing; Lrguk; OTTMUSP00000015647
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Gene Symbols: Lrguk
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Molecular weight:
93,190 Da
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Basal Isoelectric point:
5.89
Predict pI for various phosphorylation states
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