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LRGUK
Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.4.8; Kinase, other |
| Chromosomal Location of human Ortholog: 7q33 |
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Cellular Component:
acrosomal vesicle; cell projection; cytosol; manchette
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Molecular Function:
ATP binding; guanylate kinase activity; protein binding
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Biological Process:
axoneme assembly; cell differentiation; GDP metabolic process; GMP metabolic process; phosphorylation; spermatogenesis
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Reference #:
Q96M69
(UniProtKB)
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Alt. Names/Synonyms: CFAP246; FLJ32786; leucine rich repeats and guanylate kinase domain containing; Leucine-rich repeat and guanylate kinase domain-containing protein; leucine-rich repeats and guanylate kinase domain containing; LRGUK
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Gene Symbols: LRGUK
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Molecular weight:
93,618 Da
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Basal Isoelectric point:
6
Predict pI for various phosphorylation states
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