|
NUP93
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling. Belongs to the nucleoporin interacting component (NIC) family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Nucleoporin |
| Chromosomal Location of mouse Ortholog: 8|8 C5 |
|
Cellular Component:
centrosome; membrane; nuclear envelope; nuclear membrane; nuclear periphery; nuclear pore; nucleus
|
|
Molecular Function:
protein binding; structural constituent of nuclear pore
|
|
Biological Process:
mRNA transport; nuclear envelope organization; nuclear pore complex assembly; nucleocytoplasmic transport; poly(A)+ mRNA export from nucleus; positive regulation of SMAD protein signal transduction; protein import into nucleus; protein transport; SMAD protein signal transduction
|
|
Reference #:
Q8BJ71
(UniProtKB)
|
|
Alt. Names/Synonyms: 2410008G02Rik; 93 kDa nucleoporin; CBP-interacting protein 4; Cip4; Kiaa0095; Nuclear pore complex protein Nup93; nucleoporin 93; Nucleoporin Nup93; Nup93
|
|
Gene Symbols: Nup93
|
|
Molecular weight:
93,281 Da
|
|
Basal Isoelectric point:
5.5
Predict pI for various phosphorylation states
|
