NUP93 Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling. Belongs to the nucleoporin interacting component (NIC) family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Nucleoporin
Chromosomal Location of Human Ortholog: 8|8 C5
Cellular Component:  membrane; nuclear envelope; nuclear membrane; nuclear periphery; nuclear pore; nucleus
Molecular Function:  structural constituent of nuclear pore
Biological Process:  mRNA transport; nuclear envelope organization; nuclear pore complex assembly; poly(A)+ mRNA export from nucleus; positive regulation of SMAD protein signal transduction; protein import into nucleus; protein transport; renal system development; SMAD protein signal transduction
Reference #:  Q8BJ71 (UniProtKB)
Alt. Names/Synonyms: 2410008G02Rik; 93 kDa nucleoporin; CBP-interacting protein 4; Cip4; Kiaa0095; Nuclear pore complex protein Nup93; nucleoporin 93; Nucleoporin Nup93; Nup93
Gene Symbols: Nup93
Molecular weight: 93,281 Da
Basal Isoelectric point: 5.5  Predict pI for various phosphorylation states
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NUP93

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene