RAE1 Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Belongs to the WD repeat rae1 family. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; RNA-binding
Chromosomal Location of Human Ortholog: 2 H3|2 95.66 cM
Cellular Component:  cytoplasm; cytoskeleton; fibrillar center; mitotic spindle pole; nuclear envelope; nuclear pore; nucleus
Molecular Function:  RNA binding; ubiquitin binding
Biological Process:  cell cycle; cell division; cellular response to organic cyclic compound; mRNA export from nucleus; regulation of mitotic spindle organization; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
Reference #:  Q8C570 (UniProtKB)
Alt. Names/Synonyms: 3230401I12Rik; 41; D2Ertd342; D2Ertd342e; MNR; MNRP; MNRP41; mRNA export factor; mRNA-associated protein mrnp 41; Mrnp41; OTTMUSP00000018055; Rae1; Rae1 protein homolog; RAE1 RNA export 1 homolog; RAE1 RNA export 1 homolog (S. pombe); RAE1L; ribonucleic acid export 1
Gene Symbols: Rae1
Molecular weight: 40,965 Da
Basal Isoelectric point: 7.96  Predict pI for various phosphorylation states
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RAE1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene