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PRPS1L1
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. Belongs to the ribose-phosphate pyrophosphokinase family. Testis. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC 2.7.6.1; Kinase, other; Nucleotide Metabolism - purine |
| Chromosomal Location of Human Ortholog: 7p21.1 |
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Cellular Component:
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Molecular Function:
ATP binding; kinase activity; magnesium ion binding; protein homodimerization activity; ribose phosphate diphosphokinase activity
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Biological Process:
5-phosphoribose 1-diphosphate biosynthetic process; nucleoside metabolic process; phosphorylation; ribonucleoside monophosphate biosynthetic process
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Reference #:
P21108
(UniProtKB)
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Alt. Names/Synonyms: Phosphoribosyl pyrophosphate synthase 1-like 1; Phosphoribosyl pyrophosphate synthase III; phosphoribosyl pyrophosphate synthetase 1 like 1; phosphoribosyl pyrophosphate synthetase 1-like 1; phosphoribosylpyrophosphate synthetase subunit III; PRPS1; PRPS1-like 1; PRPS1L1; PRPS3; PRPSL; PRS-III; ribose-phosphate diphosphokinase catalytic chain III; Ribose-phosphate pyrophosphokinase 3; ribose-phosphate pyrophosphokinase III
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Gene Symbols: PRPS1L1
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Molecular weight:
34,839 Da
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Basal Isoelectric point:
5.92
Predict pI for various phosphorylation states
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