XPNPEP1 Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Belongs to the peptidase M24B family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 3.4.11.9; Protease
Chromosomal Location of Human Ortholog: 19|19 D2
Cellular Component:  cytoplasm; cytosol
Molecular Function:  aminopeptidase activity; hydrolase activity; manganese ion binding; metal ion binding; metalloaminopeptidase activity; metallopeptidase activity; peptidase activity; protein homodimerization activity
Biological Process:  bradykinin catabolic process; proteolysis
Reference #:  Q6P1B1 (UniProtKB)
Alt. Names/Synonyms: Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; D230045I08Rik; sAmp; Soluble aminopeptidase P; X-Pro aminopeptidase 1; X-prolyl aminopeptidase (aminopeptidase P) 1, soluble; X-prolyl aminopeptidase 1, soluble; Xaa-Pro aminopeptidase 1; Xpnpep1; XPP1
Gene Symbols: Xpnpep1
Molecular weight: 69,591 Da
Basal Isoelectric point: 5.33  Predict pI for various phosphorylation states
Select Structure to View Below

XPNPEP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene