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UROD
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. Belongs to the uroporphyrinogen decarboxylase family. Note: This description may include information from UniProtKB.
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| Protein type: Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 4.1.1.37; Lyase |
| Chromosomal Location of Human Ortholog: 4 D1|4 53.41 cM |
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Cellular Component:
cytoplasm; cytosol; nucleoplasm
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Molecular Function:
carboxy-lyase activity; ferrous iron binding; lyase activity; uroporphyrinogen decarboxylase activity
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Biological Process:
heme biosynthetic process; heme metabolic process; porphyrin-containing compound biosynthetic process; uroporphyrinogen III metabolic process
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Reference #:
P70697
(UniProtKB)
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Alt. Names/Synonyms: AI323803; DCUP; OTTMUSP00000010340; UPD; Uro; URO-D; Urod; Uroporphyrinogen decarboxylase
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Gene Symbols: Urod
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Molecular weight:
40,692 Da
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Basal Isoelectric point:
6.21
Predict pI for various phosphorylation states
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