UROD Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. Belongs to the uroporphyrinogen decarboxylase family. Note: This description may include information from UniProtKB.
Protein type: Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 4.1.1.37; Lyase
Chromosomal Location of Human Ortholog: 4 D1|4 53.41 cM
Cellular Component:  cytoplasm; cytosol; nucleoplasm
Molecular Function:  carboxy-lyase activity; ferrous iron binding; lyase activity; uroporphyrinogen decarboxylase activity
Biological Process:  heme biosynthetic process; heme metabolic process; porphyrin-containing compound biosynthetic process; uroporphyrinogen III metabolic process
Reference #:  P70697 (UniProtKB)
Alt. Names/Synonyms: AI323803; DCUP; OTTMUSP00000010340; UPD; Uro; URO-D; Urod; Uroporphyrinogen decarboxylase
Gene Symbols: Urod
Molecular weight: 40,692 Da
Basal Isoelectric point: 6.21  Predict pI for various phosphorylation states
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UROD

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene