NFL Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. Belongs to the intermediate filament family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Cellular Component:  axon; axon cytoplasm; neurofilament
Molecular Function:  identical protein binding; protein C-terminus binding; structural constituent of cytoskeleton
Biological Process:  anterograde axonal transport; axon development; axonal transport of mitochondrion; intermediate filament organization; neurofilament bundle assembly; retrograde axonal transport
Reference #:  P02547 (UniProtKB)
Alt. Names/Synonyms: 68 kDa neurofilament protein; NEFL; Neurofilament light polypeptide; neurofilament triplet L protein; NF-L; NFL
Gene Symbols: NEFL
Molecular weight: 62,072 Da
Basal Isoelectric point: 4.64  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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NFL

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene