DNAI1 Part of the dynein complex of respiratory cilia. Belongs to the dynein intermediate chain family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9p13.3
Cellular Component:  cilium; cytoskeleton; microtubule; outer dynein arm
Molecular Function:  motor activity; protein binding
Biological Process:  cilium movement; determination of left/right symmetry; flagellated sperm motility; outer dynein arm assembly
Disease: Ciliary Dyskinesia, Primary, 1
Reference #:  Q9UI46 (UniProtKB)
Alt. Names/Synonyms: Axonemal dynein intermediate chain 1; CILD1; DIC1; DNAI1; dynein axonemal intermediate chain 1; Dynein intermediate chain 1, axonemal; dynein intermediate chain DNAI1; dynein, axonemal, intermediate chain 1; dynein, axonemal, intermediate polypeptide 1; ICS; ICS1; immotile cilia syndrome 1; MGC26204; PCD; testis tissue sperm-binding protein Li 87P
Gene Symbols: DNAI1
Molecular weight: 79,283 Da
Basal Isoelectric point: 6.4  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene