AKAP4 Major structural component of sperm fibrous sheath. Plays a role in sperm motility. Belongs to the AKAP110 family. Testis specific; only expressed in round spermatids. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xp11.22
Cellular Component:  cAMP-dependent protein kinase complex; cytoskeleton; motile cilium; perinuclear region of cytoplasm; Z disc
Molecular Function:  protein binding; protein kinase A binding
Biological Process:  establishment of protein localization; flagellated sperm motility; motile cilium assembly; signal transduction; single fertilization; transmembrane receptor protein serine/threonine kinase signaling pathway
Reference #:  Q5JQC9 (UniProtKB)
Alt. Names/Synonyms: A kinase (PRKA) anchor protein 4; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; A-kinase anchoring protein 4; AKAP 82; AKAP-4; AKAP4; AKAP82; cancer/testis antigen 99; CT99; epididymis secretory sperm binding protein; FSC1; hAKAP82; HI; Major sperm fibrous sheath protein; p82; PRKA4; protein kinase A anchoring protein 4; Protein kinase A-anchoring protein 4; testis-specific gene HI
Gene Symbols: AKAP4
Molecular weight: 94,477 Da
Basal Isoelectric point: 6.56  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein