AKAP3 May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Belongs to the AKAP110 family. Testis specific; only expressed in spermatids. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Cancer Testis Antigen (CTA)
Chromosomal Location of human Ortholog: 12p13.32
Cellular Component:  acrosomal vesicle; sperm fibrous sheath; sperm principal piece
Molecular Function:  protein binding
Biological Process:  acrosome reaction; blastocyst hatching; single fertilization; transmembrane receptor protein serine/threonine kinase signaling pathway
Reference #:  O75969 (UniProtKB)
Alt. Names/Synonyms: A kinase (PRKA) anchor protein 3; A-kinase anchor protein 110 kDa; A-kinase anchor protein 3; A-kinase anchor protein, 110kDa; A-kinase anchoring protein 3; AKAP 110; AKAP-3; AKAP110; AKAP3; Cancer/testis antigen 82; CT82; epididymis luminal protein 159; epididymis secretory sperm binding protein; Fibrous sheath protein of 95 kDa; fibrous sheath protein, 95kDa; fibrousheathin 1; Fibrousheathin I; Fibrousheathin-1; FSP95; HEL159; PRKA3; protein kinase A anchoring protein 3; protein kinase A binding protein AKAP 110; Protein kinase A-anchoring protein 3; SOB1; Sperm oocyte-binding protein; sperm oocyte-binding protein 1
Gene Symbols: AKAP3
Molecular weight: 94,751 Da
Basal Isoelectric point: 5.84  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB