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SEPT1
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. Expressed at high levels in lymphoid and hematopoietic tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell cycle regulation; Cytoskeletal; Hydrolase |
| Chromosomal Location of mouse Ortholog: 7|7 F3 |
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Cellular Component:
cytoplasm; cytoskeleton; meiotic spindle; microtubule cytoskeleton; midbody; septin complex; septin ring; synaptic vesicle
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Molecular Function:
GTP binding; GTPase activity; identical protein binding; nucleotide binding
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Biological Process:
cell cycle; cell division; cytoskeleton-dependent cytokinesis; meiotic metaphase plate congression; regulation of exocytosis; spindle assembly involved in female meiosis
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Reference #:
P42209
(UniProtKB)
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Alt. Names/Synonyms: Diff; Diff6; differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase); Differentiation protein 6; OTTMUSP00000025010; Peanut-like protein 3; PNU; Pnutl3; Protein Diff6; Sep; Sept1; septin 1; Septin-1; Septin1
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Gene Symbols: Sept1
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Molecular weight:
42,020 Da
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Basal Isoelectric point:
5.59
Predict pI for various phosphorylation states
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