MYBPC1 Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family. 10 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Myosin-binding
Chromosomal Location of mouse Ortholog: 10|10 C1
Cellular Component:  cytoskeleton
Molecular Function:  myosin binding; structural constituent of cytoskeleton
Biological Process:  muscle contraction
Reference #:  Q6P6L5 (UniProtKB)
Alt. Names/Synonyms: 8030451F13Rik; MyBP-C slow; Mybpc1; myosin binding protein C, slow type; myosin binding protein C, slow-type; Myosin-binding protein C, slow-type; RIKEN cDNA 8030451F13, isoform CRA_d; Slow-type C-protein
Gene Symbols: Mybpc1
Molecular weight: 126,197 Da
Basal Isoelectric point: 5.74  Predict pI for various phosphorylation states
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MYBPC1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene