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MYBPC1
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family. 10 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Actin-binding; Myosin-binding |
| Chromosomal Location of mouse Ortholog: 10|10 C1 |
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Cellular Component:
cytoskeleton
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Molecular Function:
myosin binding; structural constituent of cytoskeleton
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Biological Process:
muscle contraction
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Reference #:
Q6P6L5
(UniProtKB)
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Alt. Names/Synonyms: 8030451F13Rik; MyBP-C slow; Mybpc1; myosin binding protein C, slow type; myosin binding protein C, slow-type; Myosin-binding protein C, slow-type; RIKEN cDNA 8030451F13, isoform CRA_d; Slow-type C-protein
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Gene Symbols: Mybpc1
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Molecular weight:
126,197 Da
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Basal Isoelectric point:
5.74
Predict pI for various phosphorylation states
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