DAP Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death. Note: This description may include information from UniProtKB.
Protein type: Autophagy
Chromosomal Location of Human Ortholog: 15|15 B2
Cellular Component: 
Molecular Function:  death domain binding
Biological Process:  activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; apoptotic signaling pathway; autophagy; cellular response to amino acid starvation; negative regulation of autophagy; negative regulation of NF-kappaB transcription factor activity; negative regulation of transcription, DNA-templated
Reference #:  Q91XC8 (UniProtKB)
Alt. Names/Synonyms: 4921531N22Rik; AI789753; AU040360; Dap; DAP-1; DAP1; death-associated protein; Death-associated protein 1; MGC19154; MGC6998
Gene Symbols: Dap
Molecular weight: 11,155 Da
Basal Isoelectric point: 9.35  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene