NOP5 Required for 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs. Belongs to the NOP5/NOP56 family. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation; Nucleolus; RNA-binding
Chromosomal Location of Human Ortholog: 2q33.1
Cellular Component:  box C/D snoRNP complex; Cajal body; cytosol; fibrillar center; nucleolus; nucleoplasm; nucleus; pre-snoRNP complex; small nucleolar ribonucleoprotein complex
Molecular Function:  ATPase binding; protein binding; snoRNA binding; TFIID-class transcription factor complex binding
Biological Process:  rRNA processing; snoRNA localization
Reference #:  Q9Y2X3 (UniProtKB)
Alt. Names/Synonyms: HSPC120; NOL5; NOP5; NOP5/NOP58; NOP58; NOP58 ribonucleoprotein homolog (yeast); Nucleolar protein 5; Nucleolar protein 58; nucleolar protein NOP5/NOP58
Gene Symbols: NOP58
Molecular weight: 59,578 Da
Basal Isoelectric point: 9.03  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene