EDC3 Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis. Belongs to the EDC3 family. Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. Note: This description may include information from UniProtKB.
Protein type: RNA processing
Chromosomal Location of mouse Ortholog: 9|9 B
Cellular Component:  cytoplasm; cytoplasmic ribonucleoprotein granule; P-body
Molecular Function:  identical protein binding; mRNA binding; RNA binding
Biological Process:  deadenylation-independent decapping of nuclear-transcribed mRNA; P-body assembly
Reference #:  Q8K2D3 (UniProtKB)
Alt. Names/Synonyms: AA517853; Edc3; enhancer of mRNA decapping 3; enhancer of mRNA decapping 3 homolog; enhancer of mRNA decapping 3 homolog (S. cerevisiae); Enhancer of mRNA-decapping protein 3; Lsm; Lsm16; Yjdc; YjeF domain-containing protein 1
Gene Symbols: Edc3
Molecular weight: 55,957 Da
Basal Isoelectric point: 6.63  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below

EDC3

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein