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GRASP
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold |
| Chromosomal Location of mouse Ortholog: 15|15 F1 |
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Cellular Component:
cytoplasm; glutamatergic synapse; membrane; nuclear envelope lumen; plasma membrane; postsynaptic density; postsynaptic membrane; Schaffer collateral - CA1 synapse; synapse
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Molecular Function:
identical protein binding; PDZ domain binding; protein binding; small GTPase binding
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Biological Process:
intracellular protein transport; regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane; signal transduction
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Reference #:
Q9JJA9
(UniProtKB)
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Alt. Names/Synonyms: General receptor for phosphoinositides 1-associated scaffold protein; Grasp; GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein; GRP1-associated scaffold protein; tamalin
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Gene Symbols: Tamalin
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Molecular weight:
42,337 Da
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Basal Isoelectric point:
9.22
Predict pI for various phosphorylation states
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