RPS8 a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Protein type: Ribosomal; Translation
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component:  cytosol; cytosolic small ribosomal subunit; endoplasmic reticulum; nucleoplasm; ribonucleoprotein complex
Biological Process:  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription
Reference #:  P62241 (UniProtKB)
Alt. Names/Synonyms: 40S ribosomal protein S8; OK/SW-cl.83; ribosomal protein S8; RPS8; RS8
Gene Symbols: RPS8
Molecular weight: 24,205 Da
Basal Isoelectric point: 10.32  Predict pI for various phosphorylation states
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RPS8

Protein Structure Not Found.


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