SEPHS1 Synthesizes selenophosphate from selenide and ATP. Belongs to the selenophosphate synthase 1 family. Class II subfamily. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.9.3; Kinase, other; Other Amino Acids Metabolism - selenoamino acid
Chromosomal Location of Human Ortholog: 2|2 A1
Cellular Component:  cytoplasm; membrane; nuclear membrane; nucleus; plasma membrane
Molecular Function:  ATP binding; identical protein binding; kinase activity; nucleotide binding; protein heterodimerization activity; protein homodimerization activity; selenide, water dikinase activity; transferase activity
Biological Process:  selenium compound metabolic process; selenocysteine biosynthetic process; tRNA seleno-modification
Reference #:  Q8BH69 (UniProtKB)
Alt. Names/Synonyms: 1110046B24Rik; AA589574; AI505014; AW111620; OTTMUSP00000011596; OTTMUSP00000011597; SELD; Selenide, water dikinase 1; Selenium donor protein 1; Selenophosphate synthase 1; selenophosphate synthetase 1; Sephs1; SPS; Sps1
Gene Symbols: Sephs1
Molecular weight: 42,907 Da
Basal Isoelectric point: 5.65  Predict pI for various phosphorylation states
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SEPHS1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene