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SEPHS1
Synthesizes selenophosphate from selenide and ATP. Belongs to the selenophosphate synthase 1 family. Class II subfamily. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.9.3; Kinase, other; Other Amino Acids Metabolism - selenoamino acid |
| Chromosomal Location of Human Ortholog: 10p13 |
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Cellular Component:
nuclear membrane; plasma membrane
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Molecular Function:
ATP binding; GTP binding; identical protein binding; protein binding
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Biological Process:
cellular protein modification process; phosphorylation
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Reference #:
P49903
(UniProtKB)
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Alt. Names/Synonyms: MGC4980; SELD; Selenide, water dikinase 1; Selenium donor protein 1; selenophosphate synthase; Selenophosphate synthase 1; selenophosphate synthetase 1; selenophosphate synthetase 1 +E9; selenophosphate synthetase 1 +E9a; selenophosphate synthetase 1 delta E2; selenophosphate synthetase 1 delta E8; selenophosphate synthetase 1 major; SEPHS1; SPS; SPS1
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Gene Symbols: SEPHS1
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Molecular weight:
42,911 Da
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Basal Isoelectric point:
5.65
Predict pI for various phosphorylation states
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