SEPHS1 Synthesizes selenophosphate from selenide and ATP. Belongs to the selenophosphate synthase 1 family. Class II subfamily. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.9.3; Kinase, other; Other Amino Acids Metabolism - selenoamino acid
Chromosomal Location of Human Ortholog: 10p13
Cellular Component:  nuclear membrane; plasma membrane
Molecular Function:  ATP binding; GTP binding; identical protein binding; protein binding
Biological Process:  cellular protein modification process; phosphorylation
Reference #:  P49903 (UniProtKB)
Alt. Names/Synonyms: MGC4980; SELD; Selenide, water dikinase 1; Selenium donor protein 1; selenophosphate synthase; Selenophosphate synthase 1; selenophosphate synthetase 1; selenophosphate synthetase 1 +E9; selenophosphate synthetase 1 +E9a; selenophosphate synthetase 1 delta E2; selenophosphate synthetase 1 delta E8; selenophosphate synthetase 1 major; SEPHS1; SPS; SPS1
Gene Symbols: SEPHS1
Molecular weight: 42,911 Da
Basal Isoelectric point: 5.65  Predict pI for various phosphorylation states
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SEPHS1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene