DDX39 Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. Belongs to the DEAD box helicase family. DECD subfamily. Note: This description may include information from UniProtKB.
Protein type: EC; Helicase; RNA splicing; RNA-binding
Chromosomal Location of Human Ortholog: 8|8 C2
Cellular Component:  nuclear speck; nucleus
Molecular Function:  ATP binding; ATPase activity; helicase activity; hydrolase activity; identical protein binding; nucleic acid binding; nucleotide binding
Biological Process:  mRNA export from nucleus; mRNA processing; mRNA splicing, via spliceosome; RNA splicing
Reference #:  Q8VDW0 (UniProtKB)
Alt. Names/Synonyms: 2610307C23Rik; ATP-dependent RNA helicase DDX39; ATP-dependent RNA helicase DDX39A; BAT1; Ddx39; DDXL; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39; DEAD box protein 39; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39; OTTMUSP00000031868; OTTMUSP00000031869; UAP56-related helicase, 49 kDa; URH49
Gene Symbols: Ddx39
Molecular weight: 49,067 Da
Basal Isoelectric point: 5.46  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene