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DDX39
Isoform 1: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. Belongs to the DEAD box helicase family. DECD subfamily. Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.6.4.13; Helicase; RNA splicing; RNA-binding |
| Chromosomal Location of mouse Ortholog: 8|8 C2 |
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Cellular Component:
cytoplasm; nuclear speck; nucleus
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Molecular Function:
ATP binding; ATP hydrolysis activity; helicase activity; hydrolase activity; identical protein binding; nucleic acid binding; nucleotide binding; RNA binding; RNA helicase activity
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Biological Process:
mRNA export from nucleus; mRNA processing; mRNA splicing, via spliceosome; RNA splicing
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Reference #:
Q8VDW0
(UniProtKB)
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Alt. Names/Synonyms: 2610307C23Rik; ATP-dependent RNA helicase DDX39; ATP-dependent RNA helicase DDX39A; BAT; BAT1; Ddx39; Ddx39a; DDXL; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39; DEAD box helicase 39a; DEAD box protein 39; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39; DX39A; OTTMUSP00000031868; OTTMUSP00000031869; UAP56-related helicase, 49 kDa; URH49
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Gene Symbols: Ddx39a
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Molecular weight:
49,067 Da
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Basal Isoelectric point:
5.46
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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