DGKB Exhibits high phosphorylation activity for long-chain diacylglycerols. Belongs to the eukaryotic diacylglycerol kinase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Kinase, lipid; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12|12 A3
Cellular Component:  cytoplasm; cytosol; glutamatergic synapse; membrane; plasma membrane; Schaffer collateral - CA1 synapse
Molecular Function:  ATP binding; calcium ion binding; diacylglycerol kinase activity; kinase activity; metal ion binding; NAD+ kinase activity; nucleotide binding; transferase activity
Biological Process:  diacylglycerol metabolic process; glycerolipid metabolic process; intracellular signal transduction; lipid phosphorylation; modulation of chemical synaptic transmission; protein kinase C-activating G protein-coupled receptor signaling pathway; regulation of postsynapse organization; response to bacterium; signal transduction
Reference #:  Q6NS52 (UniProtKB)
Alt. Names/Synonyms: 6430574F24; 90kda; C630029D13Rik; DAG kinase beta; DAGK2; DGK; DGK-bet; DGK-beta; Dgkb; Diacylglycerol kinase beta; diacylglycerol kinase, beta; Diglyceride kinase beta; Kiaa0718; mKIAA0718
Gene Symbols: Dgkb
Molecular weight: 90,272 Da
Basal Isoelectric point: 8.21  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene