TAF2 Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter. Belongs to the TAF2 family. Expressed in all tissues tested. Note: This description may include information from UniProtKB.
Protein type: Transcription initiation complex
Chromosomal Location of Human Ortholog: 15|15 D1
Cellular Component:  nucleus; transcription factor TFIID complex; transcription factor TFTC complex
Molecular Function:  chromatin binding; TFIID-class transcription factor complex binding; transcription regulatory region DNA binding
Biological Process:  G2/M transition of mitotic cell cycle; positive regulation of transcription by RNA polymerase II; transcription initiation from RNA polymerase II promoter
Reference #:  Q8C176 (UniProtKB)
Alt. Names/Synonyms: 150kD; 150kDa; 4732460C16Rik; AI425886; CIF15; CIF150; TAF(II)150; Taf2; TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF2B; TAFII; TAFII-150; TAFII150; TATA-box binding protein associated factor 2; TBP-associated factor 150 kDa; Transcription initiation factor TFIID 150 kDa subunit; Transcription initiation factor TFIID subunit 2
Gene Symbols: Taf2
Molecular weight: 126,997 Da
Basal Isoelectric point: 8.35  Predict pI for various phosphorylation states
CST Pathways:  Protein Acetylation
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene