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SEC61B
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Required for PKD1/Polycystin-1 biogenesis. Belongs to the SEC61-beta family. Note: This description may include information from UniProtKB.
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| Protein type: Endoplasmic reticulum; Membrane protein, integral |
| Chromosomal Location of human Ortholog: 9q22.33 |
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Cellular Component:
cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment; endoplasmic reticulum Sec complex; membrane; Sec61 translocon complex
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Molecular Function:
epidermal growth factor binding; protein binding; ribosome binding
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Biological Process:
post-translational protein targeting to membrane, translocation; retrograde protein transport, ER to cytosol; SRP-dependent cotranslational protein targeting to membrane, translocation; ubiquitin-dependent ERAD pathway
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Reference #:
P60468
(UniProtKB)
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Alt. Names/Synonyms: protein translocation complex beta; protein transport protein SEC61 beta subunit; Protein transport protein Sec61 subunit beta; SC61B; Sec61 beta subunit; Sec61 complex, beta subunit; SEC61 translocon beta subunit; SEC61 translocon subunit beta; SEC61B
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Gene Symbols: SEC61B
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Molecular weight:
9,974 Da
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Basal Isoelectric point:
11.57
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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