SEC61B Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Required for PKD1/Polycystin-1 biogenesis. Belongs to the SEC61-beta family. Note: This description may include information from UniProtKB.
Protein type: Endoplasmic reticulum; Membrane protein, integral
Chromosomal Location of human Ortholog: 9q22.33
Cellular Component:  cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum quality control compartment; endoplasmic reticulum Sec complex; membrane; Sec61 translocon complex
Molecular Function:  epidermal growth factor binding; protein binding; ribosome binding
Biological Process:  post-translational protein targeting to membrane, translocation; retrograde protein transport, ER to cytosol; SRP-dependent cotranslational protein targeting to membrane, translocation; ubiquitin-dependent ERAD pathway
Reference #:  P60468 (UniProtKB)
Alt. Names/Synonyms: protein translocation complex beta; protein transport protein SEC61 beta subunit; Protein transport protein Sec61 subunit beta; SC61B; Sec61 beta subunit; Sec61 complex, beta subunit; SEC61 translocon beta subunit; SEC61 translocon subunit beta; SEC61B
Gene Symbols: SEC61B
Molecular weight: 9,974 Da
Basal Isoelectric point: 11.57  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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