UBXN7 Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates. {ECO:0000269|PubMed:22537386}. Interacts with neddylated CUL2, ubiquitinated HIF1A, and VCP/p97. {ECO:0000269|PubMed:22537386}.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 3q29
Cellular Component:  cytosol; nuclear body; nucleoplasm; VCP-NPL4-UFD1 AAA ATPase complex
Molecular Function:  protein binding; transcription factor binding; ubiquitin binding; ubiquitin protein ligase binding
Biological Process:  post-translational protein modification
Reference #:  O94888 (UniProtKB)
Alt. Names/Synonyms: KIAA0794; UBX domain containing 7; UBX domain protein 7; UBX domain-containing protein 7; UBXD7; UBXN7
Gene Symbols: UBXN7
Molecular weight: 54,862 Da
Basal Isoelectric point: 5.06  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene